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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Substance Abuse Treatment and Outcomes Cellular and Molecular Neuroscience

1 paper

Safety of ibogaine administration in detoxification of opioid‐dependent individuals: a descriptive open‐label observational study

Thomas Knuijver, Arnt Schellekens, Maarten Belgers, Rogier Donders, Toon van Oosteren, Cornelis Kramers, et al.
Addiction Summary & key facts 2021 45 citations

A descriptive open-label observational study of ibogaine in people with opioid use disorder found the drug can produce clear but reversible heart and nervous-system side effects. Reported effects included QTc prolongation (a change in the heart’s electrical timing), slow heart rate (bradycardia), and severe problems with balance and coordination (ataxia).…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Neurotransmitter Receptor Influence on Behavior Substance Abuse Treatment and Outcomes
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.