Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

2 papers

Vagal Sensory Neuron Subtypes that Differentially Control Breathing

Rui B. Chang, David E. Strochlic, Erika K. Williams, Benjamin D. Umans, Stephen D. Liberles
PubMed Summary & key facts 2015 429 citations

Researchers studied mouse vagus nerve cells and found two small, separate groups of sensory neurons (called P2ry1 and Npy2r). Each group has only a few hundred neurons and sends dense branches into the lung but to different brainstem areas. Using optogenetics (light to activate chosen neurons), turning on P2ry1 neurons…

Neuroendocrine regulation and behavior Neuroscience of respiration and sleep Vagus Nerve Stimulation Research

Vaping additives cannabinoid oil and vitamin E acetate adhere to and damage the human airway epithelium

Boris Reidel, Sabri H. Abdelwahab, Joe A. Wrennall, Phillip W. Clapp, Jessica L. Beers, Klarissa D. Jackson, et al.
PubMed Summary & key facts 2023 8 citations

Researchers exposed human airway epithelial cell cultures to vaping aerosols made from common e-liquid base (PG/VG), PG/VG with CBD oil, and PG/VG with CBD oil plus vitamin E acetate (VEA). They saw CBD oil and VEA stick to the airway surface and build up inside cells. After three daily exposures,…

Chronic Obstructive Pulmonary Disease (COPD) Research Neuroscience of respiration and sleep Respiratory and Cough-Related Research
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