Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
This review looked at randomized trials and previous reviews up to August 2018 to see how cannabis-based medicines work for mental disorders. The authors found some symptom improvements when THC- or CBD-containing medicines were added to usual treatments, but they did not find evidence these medicines led to remission. Side…
This review summarizes evidence on harms from recreational cannabis and on medical uses of cannabinoids. It says regular use of high-THC cannabis can lead to cannabis use disorder (addiction). Single high doses can cause short-term mental, stomach, and heart problems and raise the risk of car crashes. Long-term or heavy…
This case-control study compared 163 depressed in-patients (44% women) with 176 controls (51% women). Using a median split on the Male Depression Rating Scale‑22 to label 'masculine' versus 'non-masculine' depression, the study found that masculine depression was linked to worse depression, more frequent and heavy use of alcohol (including binge…
