Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
Treatment-resistant depression means depression that does not get better after usual treatments. Scientists do not all agree on one clear definition, which makes it hard to know exactly how common it is or which treatments work best. Using the definition that regulators often use, about 30% of people with depression…
This large review combined 441 randomized trials with 33,881 patients to measure how many people show a clear response to psychotherapy across eight mental disorders. Response was defined as at least a 50% reduction in symptoms from before to after treatment. Pooled response rates were modest (for example, about 42%…
