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Researchers reviewed about 300 studies and closely read 29 that tested how ketamine changes the brain at the molecular level in post-traumatic stress disorder (PTSD). They looked at short-term changes that happen while the drug is active and longer-term changes that can last after the drug is gone. Short-term changes…
Researchers gave a low dose of esketamine through an IV before general anesthesia to 200 adults having planned orthopedic surgery. They compared 100 people who got esketamine with 100 who got a saline placebo. The esketamine group showed smaller rises in inflammatory proteins after surgery, higher levels of antibodies, less…
