The Neurobiology of Pathological Fatigue: New Models, New Questions
This review compares three recent brain-based ideas for pathological fatigue and the evidence for them. One idea, the sensory attenuation model (SAF), says poor suppression of self-generated sensory signals makes movements feel harder and so raises perceived effort; a study found that long-term (trait) fatigue, but not day-to-day (state) fatigue,…