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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Diet, Metabolism, and Disease Medicine Alternative medicine

2 papers

Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study

Khalid Jadoon, S. Ratcliffe, David A. Barrett, E. Louise Thomas, Colin Stott, Jimmy D. Bell, et al.
Diabetes Care Summary & key facts 2016 246 citations

This was a small, randomized, double-blind, placebo-controlled 13-week pilot trial of two nonpsychoactive cannabis-related compounds (cannabidiol, CBD, and tetrahydrocannabivarin, THCV) in 62 people with type 2 diabetes who were not using insulin. Participants were assigned to CBD, THCV, two CBD/THCV combination doses, or placebo. Compared with placebo, THCV lowered fasting…

Cannabis and Cannabinoid Research Diet, Metabolism, and Disease Pancreatic function and diabetes

Weight Loss and Therapeutic Metabolic Effects of Tetrahydrocannabivarin (THCV)-Infused Mucoadhesive Strips

Gregory L. Smith
Cannabis Summary & key facts 2024 2 citations

A placebo-controlled study of 44 adults (average age 51.8) tested daily mucoadhesive oral strips containing THCV and CBD for 90 days. Both the lower dose (8 mg THCV/10 mg CBD) and the higher dose (16 mg THCV/20 mg CBD) were associated with statistically significant weight loss versus placebo, and the…

Cannabis and Cannabinoid Research Diet, Metabolism, and Disease GABA and Rice Research
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