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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Parkinson's Disease Mechanisms and Treatments Medicine Clinical trial

1 paper

Deep Brain Stimulation in Treatment-Resistant Depression: A Systematic Review and Meta-Analysis on Efficacy and Safety

Youliang Wu, Jiajie Mo, Lisen Sui, Jianguo Zhang, Wenhan Hu, Chao Zhang, et al.
Frontiers in Neuroscience Summary & key facts 2021 74 citations

This review combined 17 studies of deep brain stimulation (DBS) for people with treatment-resistant depression. Across studies, about 56% of patients showed a clinical response and 35% reached remission, while 14% later had recurrence. Adverse events were common (about 67%), and the two randomized trials did not show a clear,…

Neurological disorders and treatments Parkinson's Disease Mechanisms and Treatments Transcranial Magnetic Stimulation Studies
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