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21 papers
Our findings suggest that geographic location plays a limited role in the reasons for the large variability of ADHD/HD prevalence estimates worldwide. Instead, this variability seems to be explained primarily by the methodological characteristics of studies.
This umbrella review pooled evidence from 97 systematic reviews (1,039 randomized trials, 128,119 participants) to examine whether physical activity affects symptoms of depression, anxiety and psychological distress in adults. Overall, physical activity produced medium-sized reductions in symptoms (median effect size for depression = -0.43, for anxiety = -0.42; distress effect…
The authors pooled results from 61 cross-sectional studies to estimate how common ADHD is in children and adolescents worldwide. They found a pooled prevalence of 7.6% (95% CI 6.1–9.4%) in children aged 3–12 (from 96,907 children) and 5.6% (95% CI 4.8–7%) in adolescents aged 12–18. Prevalence estimates varied by age…
This 2019 systematic review looked at human studies of medicinal cannabis and cannabis-derived isolates for major psychiatric disorders. The authors found that the evidence is very new and limited, so it is too early to recommend cannabis medicines for psychiatric conditions. Some small or isolated studies suggest benefits for a…
The CANMAT 2023 update gives doctors clear, up-to-date advice for treating adults with major depressive disorder. It puts evidence into a practical, clinician-friendly format. The update says treatment should be a team effort between patients and clinicians, be tailored to each person, and follow a planned, systematic process with regular…
This systematic review looked at 83 published reports on ketamine for mental health and substance use disorders. It found strong evidence that ketamine can produce rapid antidepressant and anti‑suicidal effects, but these benefits tend to be short‑lived. Evidence for other conditions was weaker but often showed similar short-term effects. Many…
This systematic review looked at what happens when women live with undiagnosed ADHD and what changes after they get diagnosed as adults. The authors searched three databases and kept eight studies. They used thematic analysis and found four main themes: harms to social and emotional wellbeing, hard or strained relationships,…
This large review combined 441 randomized trials with 33,881 patients to measure how many people show a clear response to psychotherapy across eight mental disorders. Response was defined as at least a 50% reduction in symptoms from before to after treatment. Pooled response rates were modest (for example, about 42%…
This systematic review looked at 17 studies with a total of 603 participants on ketamine-assisted psychotherapy (KAP). The reviewed reports say KAP can, in some cases, start and lengthen meaningful reductions in pain, anxiety, and depression, and help with rapport, treatment engagement, and abstinence for people with substance problems. However,…
The results concerning effectiveness and method-specific key factors of SE are promising; yet, require more support from unbiased RCT-research. Future research should focus on filling this gap.
This systematic review examined human studies of plant-derived nootropics across six cognitive domains. It included 256 papers published from January 2000 to November 2021 found via PubMed, Cochrane and Scopus. The review reports that Ginkgo biloba was most relevant for perceptual and motor functions, Bacopa monnieri improved language, learning and…
