Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

4 papers

Effects of voluntary slow breathing on heart rate and heart rate variability: A systematic review and a meta-analysis

Sylvain Laborde, Mark S. Allen, Uirassu Borges, Fabrice Dosseville, Thomas J. Hosang, Maša Iskra, et al.
PubMed Summary & key facts 2022 205 citations

This 2022 systematic review and meta-analysis pooled data from 223 studies to see if voluntary slow breathing (VSB) changes heart rate variability that reflects parasympathetic (vagal) control of the heart. The authors found that VSB increased vagally-mediated heart rate variability during breathing sessions, right after a single session, and after…

Cardiac Health and Mental Health Cardiovascular and exercise physiology Heart Rate Variability and Autonomic Control

Mental health disorders and their impact on cardiovascular health disparities

Viola Vaccarino, Eva Prescott, Amit J Shah, J Douglas Bremner, Paolo Raggi, Olivija Dobiliene, et al.
PubMed Central (PMC) Summary & key facts 2025 7 citations

This review found that mental health disorders are common and closely linked with worse heart health. People with conditions like depression, anxiety, schizophrenia, bipolar disorder, or PTSD have higher rates of cardiovascular disease and higher death rates from it. The reasons include biology, behaviours, and problems in health care. The…

Cardiac Health and Mental Health Health, psychology, and well-being Mental Health Treatment and Access

Walking Psychotherapy As a Health Promotion Strategy to Improve Mental and Physical Health for Patients and Therapists: Clinical Open-Label Feasibility Trial

Nicole Koziel, Simone N. Vigod, Jennifer Price, Joanne Leung, Jennifer Hensel
PubMed Summary & key facts 2022 7 citations

This small open-label study tested whether therapists and patients could walk outside during trauma therapy sessions. Most people joined and found walking acceptable. Walking happened in about two-thirds of sessions. Some PTSD and stress scores were lower after 12 weeks, but the study had no control group and further randomized…

Cardiac Health and Mental Health Physical Activity and Health Traumatic Brain Injury Research

Examining the needs, outcomes and current treatment pathways of 2461 people with treatment-resistant depression: mixed-methods study

Kiranpreet Gill, Danielle Hett, Max Carlish, Rebekah Amos, Ali Khatibi, Isabel Morales-Muñoz, et al.
Cambridge Core Summary & key facts 2026 5 citations

This mixed-methods study used NHS electronic health records and interviews to look at people with major depressive disorder in one large UK trust. Using a common definition of treatment-resistant depression (failure to respond to at least two antidepressant trials), the researchers found TRD was common (48% of the sample) and…

Cardiac Health and Mental Health Mental Health Treatment and Access Treatment of Major Depression
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.