Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

30 papers

The Prevalence and Correlates of Adult ADHD in the United States: Results From the National Comorbidity Survey Replication

Ronald C. Kessler
American Journal of Psychiatry Summary & key facts 2006 2,956 citations

This U.S. study used a nationally representative household survey of 3,199 adults aged 18–44, plus clinical follow-up interviews, to measure adult ADHD. Researchers estimated that 4.4% of adults had current ADHD. Adult ADHD was more common in men, people who were previously married, those who were unemployed, and non-Hispanic white…

Attention Deficit Hyperactivity Disorder Child and Adolescent Psychosocial and Emotional Development Functional Brain Connectivity Studies

Females with ADHD: An expert consensus statement taking a lifespan approach providing guidance for the identification and treatment of attention-deficit/ hyperactivity disorder in girls and women

Susan Young, Nicoletta Adamo, Bryndís Björk Ásgeirsdóttir, Polly Branney, Michelle Beckett, William Colley, et al.
BMC Psychiatry Summary & key facts 2020 431 citations

This ADDA article explains ADHD masking — when people hide or copy others to appear "normal." Masking can help someone function but often uses a lot of mental and emotional energy. The article says masking can delay diagnosis, cause burnout or mood problems, and may help explain why women are…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research Child and Adolescent Psychosocial and Emotional Development

Gender effects on Attention-Deficit/Hyperactivity disorder in adults, revisited

Joseph Biederman, Stephen V. Faraone, Michael C. Monuteaux, Marie Bober, Elizabeth Cadogen
Biological Psychiatry Summary & key facts 2004 380 citations

This study reexamined gender differences in adult ADHD by comparing 219 adults with ADHD to 215 control subjects matched for age and gender. The researchers found no evidence that gender changed how ADHD related to other psychiatric disorders. Adults with ADHD showed cognitive deficits and higher rates of major depression,…

Attention Deficit Hyperactivity Disorder Child and Adolescent Psychosocial and Emotional Development Functional Brain Connectivity Studies

Racial and Ethnic Disparities in ADHD Diagnosis From Kindergarten to Eighth Grade

Paul L. Morgan, Jeremy Staff, Marianne M. Hillemeier, George Farkas, Steve Maczuga
PEDIATRICS Summary & key facts 2013 290 citations

This study followed a nationally representative group of U.S. children who started kindergarten in 1998–99 to track ADHD diagnosis from kindergarten through eighth grade. It found that racial and ethnic minority children were less likely than white children to be diagnosed by kindergarten and that these differences continued through eighth…

Attention Deficit Hyperactivity Disorder Child and Adolescent Psychosocial and Emotional Development Infant Development and Preterm Care

A meta-analysis of the prevalence of attention deficit hyperactivity disorder in incarcerated populations

Susan Young, Donald Moss, Ottilie Sedgwick, Moshe Fridman, P. Hodgkins
Psychological Medicine Summary & key facts 2014 277 citations

The authors combined results from 42 studies of people in prison to estimate how common ADHD is in those groups. Using formal diagnostic interviews, the overall ADHD rate was about 25.5%. Reported rates were higher when studies used screening tools or when adults recalled childhood ADHD. The review found much…

Attention Deficit Hyperactivity Disorder Bipolar Disorder and Treatment Child and Adolescent Psychosocial and Emotional Development

Cognitive behavioral interventions for alcohol and drug use disorders: Through the stage model and back again.

Kathleen M. Carroll, Brian D. Kiluk

Cognitive behavioral therapy (CBT) is one of the most-studied treatments for alcohol and drug problems. Reviews of many trials find a small but real average benefit: a meta-analysis of 53 controlled trials reported an effect size of g = 0.15 and estimated that 58% of people given CBT did better…

Child and Adolescent Psychosocial and Emotional Development Mental Health Research Topics Substance Abuse Treatment and Outcomes

Postpartum stress and infant outcome: A review of current literature

Aderonke Oyetunji, Prakash Chandra
Psychiatry Research Summary & key facts 2020 196 citations

This paper is a systematic review of 74 English-language studies from 1995–2019 that looked at how postpartum stress, including depressive and anxiety symptoms in mothers, is linked to infant outcomes. The review found consistent associations between higher postpartum stress and worse infant growth, development, feeding, attachment and sleep. The authors…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

Acute Marijuana Effects on Human Risk Taking

Scott D. Lane, Don R. Cherek, Oleg V Tcheremissine, Lori M. Lieving, Cythia J Pietras
Neuropsychopharmacology Summary & key facts 2005 172 citations

Researchers gave 10 adults placebo cigarettes and three active marijuana cigarettes (including a 3.58% Delta9-THC dose) in a repeated-measures lab test. Using a task that forced a choice between a risky and a nonrisky option, the highest THC dose made people choose the risky option more often. The same high…

Cannabis and Cannabinoid Research Child and Adolescent Psychosocial and Emotional Development Substance Abuse Treatment and Outcomes

Depression and Mania in Bipolar Disorder

Leonardo Tondo, Gustavo H Vázquez, Ross J Baldessarini
PubMed Central (PMC) Summary & key facts 2017 167 citations

Researchers reviewed records from 1,130 people with bipolar disorder seen at a mood-disorders center. They found that depressive episodes lasted much longer than manic episodes, and that episode length was similar across bipolar subtypes (BD-I, BD-II, mixed, or with psychosis). The authors say this pattern — more and longer depressions…

Bipolar Disorder and Treatment Child and Adolescent Psychosocial and Emotional Development Schizophrenia research and treatment

Treatment of post-partum depression: a review of clinical, psychological and pharmacological options

Kristin Leight, Elizabeth Fitelson, Sarah Kim, Allison S. Baker

Postpartum depression (PPD) is a common problem after childbirth. Most studies find rates around 10%–15% in high-income countries, and rates can be much higher in poorer settings. Untreated PPD is linked with problems in mother–baby bonding and with worse child development. Screening in routine obstetric, pediatric, or primary care visits…

Breastfeeding Practices and Influences Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum

Use of cannabidiol in anxiety and anxiety-related disorders

Jessica W. Skelley, Crystal M. Deas, Zachary Curren, Jonathan Ennis
PubMed Summary & key facts 2020 133 citations

This systematic review looked at human studies of cannabidiol (CBD) for anxiety up to June 2019. Eight studies were included (6 small randomized controlled trials, 1 case series, and 1 case report). The studies tested CBD for anxiety in healthy volunteers, generalized anxiety disorder, social anxiety disorder, and PTSD-related anxiety.…

Bipolar Disorder and Treatment Cannabis and Cannabinoid Research Child and Adolescent Psychosocial and Emotional Development

Miss. Diagnosis: A Systematic Review of ADHD in Adult Women

Darby E. Attoe, Emma A. Climie
Journal of Attention Disorders Summary & key facts 2023 118 citations

This systematic review looked at what happens when women live with undiagnosed ADHD and what changes after they get diagnosed as adults. The authors searched three databases and kept eight studies. They used thematic analysis and found four main themes: harms to social and emotional wellbeing, hard or strained relationships,…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research Child and Adolescent Psychosocial and Emotional Development
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