Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.
In healthy adults from the general population, we found a significant and robust association between depression and anemia. Further studies are needed to assess the longitudinal relationship between both conditions and determine the mechanisms underlying this association.
This was a single-blinded, randomized trial of 290 premenopausal women with unexplained fatigue and low iron who received one 1000 mg IV dose of ferric carboxymaltose (FCM) or saline placebo. By Day 56, more women given FCM had reduced fatigue and larger improvements in some quality-of-life and cognitive scores, and…
This population study used Taiwan's national health insurance records to compare adults with iron deficiency anemia (IDA) to matched people without IDA from 2000–2013. After adjusting for other factors, people with IDA had a higher risk of being diagnosed with psychiatric disorders (adjusted hazard ratio 1.52, 95% CI 1.45–1.59). The…
This cross-sectional study looked at 200 people aged 16–60 in rural India who had depression and iron deficiency anaemia. It found that lower haemoglobin and other red blood cell measures were linked to worse depression scores. Over half (55.5%) had severe depression, and the authors say treating anaemia alongside depression…
