Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

5 papers

A comprehensive review of the psychological effects of brainwave entrainment.

PubMed 2009 179 citations

This paper reviewed 20 peer-reviewed studies on brainwave entrainment (BWE). BWE uses rhythmic sounds or flashes of light to change brainwave frequencies. The review found that BWE appears to help with thinking problems, stress and anxiety, pain, headaches or migraines, mood and behavior issues, and premenstrual syndrome. The authors say…

Infant Health and Development Menstrual Health and Disorders Neuroendocrine regulation and behavior

Brexanolone to Treat Postpartum Depression in Adult Women

Elyse M. Cornett, Lauren Rando, Austin M Labbé, Wil Perkins, Adam M. Kaye, Alan D. Kaye, et al.
Psychopharmacology Bulletin Summary & key facts 2025 32 citations

Brexanolone (brand name ZULRESSO) is an FDA-approved drug for moderate-to-severe postpartum depression. In trials it reduced depressive symptoms quickly and had mostly mild side effects, but it is given by IV in a monitored inpatient setting because it can cause heavy sleepiness and even loss of consciousness. It is not…

Maternal Mental Health During Pregnancy and Postpartum Neuroendocrine regulation and behavior Stress Responses and Cortisol

Postpartum Depression: Etiology, Treatment, and Consequences for Maternal Care

Daiana Anne‐Marie Dimcea, Răzvan Petca, Mihai Cristian Dumitrașcu, Florica Şandru, Claudia Mehedințu, Aida Petca
Diagnostics Summary & key facts 2024 31 citations

This review says postpartum depression (PPD) is a common and disabling problem that has been rising in many places. It summarizes known risk factors in social and economic life, childbirth history, lifestyle, and past mental illness. The paper also reviews biological and genetic work (the serotonin transporter gene, SERT, is…

Child and Adolescent Psychosocial and Emotional Development Maternal Mental Health During Pregnancy and Postpartum Neuroendocrine regulation and behavior

Serotonergic, Dopaminergic, and Noradrenergic Modulation of Erotic Stimulus Processing in the Male Human Brain

Heiko Graf, Kathrin Malejko, Coraline D. Metzger, Martin Walter, Georg Grön, Birgit Abler
Journal of Clinical Medicine Summary & key facts 2019 25 citations

This review explains how the brain controls sexual responses and how three neurotransmitter systems (serotonin, dopamine, noradrenaline) can change brain activity during erotic stimulation. The authors describe brain networks for different parts of sexual arousal (thinking/appraisal, feeling/pleasure, wanting/goal-directed, and bodily/autonomic responses). They also say pharmaco-fMRI (brain scans after giving drugs)…

Hypothalamic control of reproductive hormones Neuroendocrine regulation and behavior Sexual function and dysfunction studies

Does Bupropion Impact More than Mood? A Case Report and Review of the Literature

Waqas Yasin, Syed Ijlal Ahmed, Robert V Gouthro
Cureus Summary & key facts 2019 9 citations

This article describes one patient who developed increased sexual urges after bupropion was added to his ongoing fluoxetine treatment. The urges dropped after bupropion was stopped and replaced with mirtazapine. The authors review other studies showing bupropion usually causes fewer sexual problems than SSRIs but can sometimes raise libido, and…

Neuroendocrine regulation and behavior Sexual function and dysfunction studies Treatment of Major Depression
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.