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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Neuroscience Audiology Human Brain Mapping

1 paper

Ketamine effects on default mode network activity and vigilance: A randomized, placebo‐controlled crossover simultaneous fMRI/EEG study

Norman Zacharias, Francesco Musso, Felix Müller, Florian Lammers, Andreas Saleh, Markus K. London, et al.
Human Brain Mapping Summary & key facts 2019 65 citations

This randomized, double-blind, placebo-controlled crossover study gave subanesthetic S‑ketamine to 24 healthy young people while recording fMRI and EEG at rest. After ketamine, fMRI showed less connectivity in the medial prefrontal cortex and more connectivity in left and right intraparietal (parietal) areas of the default mode network. EEG showed more…

Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies Treatment of Major Depression
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.