Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

2 papers

Long-Term Occupational Stress Is Associated with Regional Reductions in Brain Tissue Volumes

Eva Blix, Aleksander Perski, Hans Berglund, Ivanka Savic
PLoS ONE Summary & key facts 2013 131 citations

Several brain-imaging studies found that people with long-term work-related burnout showed differences in brain structure and function compared with matched healthy adults. In groups where participants had worked more than about 60–70 hours per week for several years, researchers reported larger amygdala size, thinner medial prefrontal cortex (mPFC) tissue, weaker…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Functional Brain Connectivity Studies Stress Responses and Cortisol

Reward-related self-agency is disturbed in depression and anxiety

Marishka Mehta, Soojung Na, Xiaosi Gu, James W. Murrough, Laurel Morris
PLoS ONE Summary & key facts 2023 5 citations

Researchers tested a new task that measures how people feel they caused rewards or losses. They studied 52 healthy adults and 20 adults with depression or anxiety in person, and 254 people online. Healthy people felt more personal control after wins than after losses. People with depression or anxiety showed…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Neural and Behavioral Psychology Studies Psychosomatic Disorders and Their Treatments
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