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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Tryptophan and brain disorders Neuroscience Translational Psychiatry

1 paper

Peripubertal stress increases play fighting at adolescence and modulates nucleus accumbens CB1 receptor expression and mitochondrial function in the amygdala

Aurélie Papilloud, Isabelle Guillot de Suduiraut, Olivia Zanoletti, Jocelyn Grosse, Carmen Sandi
Translational Psychiatry Summary & key facts 2018 40 citations

This rat study tested whether stress during the peripuberty period (seven non-consecutive days between postnatal day 28 and 42) changed play fighting at adolescence and later brain markers. Rats exposed to peripubertal stress showed more play fighting at P45. The researchers found that animals with very high play fighting in…

Neuroendocrine regulation and behavior Stress Responses and Cortisol Tryptophan and brain disorders
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