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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Nerve injury and regeneration Neuroscience Chemistry

1 paper

Ibogaine Administration Modifies GDNF and BDNF Expression in Brain Regions Involved in Mesocorticolimbic and Nigral Dopaminergic Circuits

Marton, Soledad, González, Bruno, Rodríguez-Bottero, Sebastián, et al.
www.frontiersin.org Summary & key facts 2019 65 citations

In this rat study, animals got a single injection of ibogaine at 20 mg/kg or 40 mg/kg and the researchers measured three neurotrophic factors (GDNF, BDNF, NGF) in four brain regions (VTA, prefrontal cortex, nucleus accumbens, substantia nigra) at 3 and 24 hours. The main changes appeared at 24 hours:…

Nerve injury and regeneration Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies
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