Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

2 papers

Impact of anxiety on prefrontal cortex encoding of cognitive flexibility

Junchol Park, Bita Moghaddam
Neuroscience Summary & key facts 2016 221 citations

This review looks at studies in humans and animals that link anxiety and stress with poorer cognitive flexibility — the ability to change strategies when rules or goals change. It describes evidence that the prefrontal cortex (PFC) is central to flexible behavior, that anxiety or PFC disruptions are associated with…

Memory and Neural Mechanisms Neural and Behavioral Psychology Studies Stress Responses and Cortisol

Creatures of Habit: The Neuroscience of Habit and Purposeful Behavior

Alana I. Mendelsohn
Biological Psychiatry Summary & key facts 2019 16 citations

This article explains that much of everyday behavior comes from habits, which are triggered by cues and run automatically, while goal-directed actions are based on expected outcomes and are more flexible. Brain studies show these two strategies use different but connected circuits: a prefrontal–dorsomedial striatum loop for goal-directed control and…

Attention Deficit Hyperactivity Disorder Neural and Behavioral Psychology Studies Neuroscience, Education and Cognitive Function
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