Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

1 paper

Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review

Zach Walsh, Özden Merve Mollaahmetoğlu, Joseph M. Rootman, Shannon Golsof, Johanna Louise Keeler, Beth Marsh, et al.
BJPsych Open Summary & key facts 2021 168 citations

This systematic review looked at 83 published reports on ketamine for mental health and substance use disorders. It found strong evidence that ketamine can produce rapid antidepressant and anti‑suicidal effects, but these benefits tend to be short‑lived. Evidence for other conditions was weaker but often showed similar short-term effects. Many…

Mental Health Research Topics Treatment of Major Depression Tryptophan and brain disorders Ketamine
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