Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

2 papers

Acute effects of a standardised extract of Hericium erinaceus (Lion’s Mane mushroom) on cognition and mood in healthy younger adults: a double-blind randomised placebo-controlled study

Surendran, Geyan, Saye, Jake, Binti Mohd Jalil, Syahira, et al.
www.frontiersin.org Summary & key facts 2025 4 citations

This double-blind, randomised, placebo-controlled study tested a single (acute) dose of a standardized extract from the Lion’s Mane mushroom (fruiting body) in healthy younger adults. The study did not find a clear overall benefit for thinking skills or mood compared with placebo. The authors say any small benefits might only…

Fungal Biology and Applications Medicinal Plants and Bioactive Compounds Pharmacological Effects of Natural Compounds

Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review

Akshay Menon, Ayesha Jalal, Zara Arshad, Faisal A. Nawaz, Rahul Kashyap
Frontiers in Nutrition Summary & key facts 2025 3 citations

This systematic review looked at 26 studies on Lion’s Mane (Hericium erinaceus) published up to June 2024. The authors found some clinical trial evidence of small cognitive improvements (a combined MMSE increase of 1.17 from one RCT and one pilot trial), laboratory evidence of anti‑cancer activity in cell lines, and…

Fungal Biology and Applications Ginseng Biological Effects and Applications Medicinal Plants and Bioactive Compounds
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