Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

24 papers

Nature and mental health: An ecosystem service perspective

Gregory N. Bratman, Christopher B. Anderson, Marc G. Berman, B.J. Cochran, S. de Vries, Jon Flanders, et al.
Science Advances Summary & key facts 2019 1,741 citations

This review sums up research showing that being in or exposed to nature is linked to better mental functioning and mood. Lab and field experiments find short-term improvements in stress and mood from nature sights, sounds, and walks in green places. Population studies also find people living near green or…

Land Use and Ecosystem Services Urban Agriculture and Sustainability Urban Green Space and Health

The health benefits of the great outdoors: A systematic review and meta-analysis of greenspace exposure and health outcomes

Caoimhe Twohig-Bennett, Andy Jones
PubMed Summary & key facts 2018 1,542 citations

This review combined 143 studies (103 observational and 40 intervention) that looked at about 100 health outcomes to see how contact with greenspace relates to health. Overall, more greenspace exposure was linked with lower stress markers, lower heart rate and some lower blood pressure, and with lower risks for outcomes…

Noise Effects and Management Urban Green Space and Health Urban Heat Island Mitigation

Muscle fatigue: what, why and how it influences muscle function

Roger M. Enoka, Jacques Duchateau
The Journal of Physiology Summary & key facts 2007 1,374 citations

This review explains that muscle fatigue can come from many different causes and that there is no single global cause. Fatigue is usually measured as a drop in the maximum force or power a muscle can make, but people can still do less-demanding tasks after that drop begins. Which processes…

Motor Control and Adaptation Muscle activation and electromyography studies Sports Performance and Training

Green space exposure on depression and anxiety outcomes: A meta-analysis

Ziquan Liu, Xuemei Chen, Huanhuan Cui, Yuxuan Ma, Ning Gao, Xinyu Li, et al.
PubMed Summary & key facts 2023 118 citations

This meta-analysis of observational studies found that higher exposure to green space was linked with slightly lower odds of depression and possibly lower odds of anxiety. A 10% increase in the amount of green space was associated with lower odds of depression (OR 0.963; 95% CI 0.948–0.979) and with a…

Land Use and Ecosystem Services Urban Agriculture and Sustainability Urban Green Space and Health

Gardening for health: a regular dose of gardening

Richard Thompson
Clinical Medicine Summary & key facts 2018 97 citations

There is increasing evidence that exposure to plants and green space, and particularly to gardening, is beneficial to mental and physical health, and so could reduce the pressure on NHS services. Health professionals should therefore encourage their patients to make use of green space and to work in gardens, and…

Climate Change and Health Impacts Therapeutic Uses of Natural Elements Urban Green Space and Health

Combined Effect of Walking and Forest Environment on Salivary Cortisol Concentration

Kobayashi, Hiromitsu, Song, Chorong, Ikei, Harumi, et al.
www.frontiersin.org Summary & key facts 2019 87 citations

Seventy-four young men walked for 15 minutes in both a forest and an urban area, with saliva taken before and after each walk. Mean salivary cortisol dropped after the forest walk (from 9.70 to 8.37 nmol/L) but hardly changed after the urban walk (from 10.28 to 10.01 nmol/L). Statistical tests…

Stress Responses and Cortisol Urban Green Space and Health

A Systematic Review and Meta-Analysis of Nature Walk as an Intervention for Anxiety and Depression

Simone Grassini
PubMed Summary & key facts 2022 53 citations

This review looked at studies from the past decade on whether walking in nature affects depression and anxiety. Seven studies met the review rules, and data from six experiments were combined in a meta-analysis. The pooled results showed reductions in depression and anxiety symptoms after nature walks, both when people…

Art Therapy and Mental Health Child Therapy and Development Urban Green Space and Health

Do Wellness Tourists Get Well? An Observational Study of Multiple Dimensions of Health and Well-Being After a Week-Long Retreat

Marc Cohen, Fiona Elliott, Liza Oates, Adrian Schembri, Nitin Mantri

Researchers followed 37 people who attended a one-week residential wellness retreat in rural Queensland. They measured many health and well-being outcomes on arrival, at departure, and again 6 weeks later (17 people were followed at 6 weeks). After one week, participants showed statistically significant improvements in most measures, including weight,…

Complementary and Alternative Medicine Studies Outdoor and Experiential Education Urban Green Space and Health

Nature and Mindfulness to Cope with Work-Related Stress: A Narrative Review

Elisa Menardo, Donatella Di Marco, Sara Ramos, Margherita Brondino, Alicia Arenas, Patricia Costa, et al.
PubMed Central (PMC) Summary & key facts 2022 50 citations

This review says work-related stress has grown and harms both workers (for example, depression and anxiety) and companies (for example, more absenteeism and lower productivity). It describes two prevention approaches: individual approaches that teach coping and resilience (including mindfulness) and organizational changes that alter work conditions (including adding natural elements).…

Animal and Plant Science Education Educational Environments and Student Outcomes Urban Green Space and Health

The Potential for Outdoor Nature-Based Interventions in the Treatment and Prevention of Depression

Owens, Matthew, Bunce, Hannah L. I.
www.frontiersin.org Summary & key facts 2022 40 citations

This paper is a conceptual review about using outdoor, nature-based interventions (NBIs) to help prevent and treat depression. It does not present new trial data but argues we need to know the specific “active ingredients” that might make NBIs helpful. The authors list five possible mechanisms (stress, rumination, mindfulness, sleep,…

Behavioral Health and Interventions Outdoor and Experiential Education Urban Green Space and Health

oVRcome – Self-guided virtual reality for specific phobias: A randomised controlled trial

Cameron Lacey, Chris Frampton, Ben Beaglehole

Self-guided use of the oVRcome app was effective at reducing severity of specific phobia symptoms in a sample of people with a self-reported fear of flying, heights, spiders, dogs or needles.Trial registry clinicaltrials.gov NCT04909177.

Mind wandering and attention Pain Management and Placebo Effect Virtual Reality Applications and Impacts

Harnessing the Four Elements for Mental Health

Jerome Sarris, Michael de Manincor, Fiona Hargraves, Jack Tsonis
PubMed Summary & key facts 2019 21 citations

This 2019 scoping review explores how the four classical elements—Fire, Water, Earth, and Air—can map onto modern, changeable exposures and therapies that might affect mental health. The authors summarize emerging evidence from both population studies and intervention trials for things like UV or heat therapy (Fire), sauna and hydrotherapy (Water),…

Complementary and Alternative Medicine Studies Mindfulness and Compassion Interventions Urban Green Space and Health
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