Frontier mental health research: psychedelics & drug studies

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60 papers

The Worldwide Prevalence of ADHD: A Systematic Review and Metaregression Analysis

Guilherme V. Polanczyk, Maurício Silva de Lima, Bernardo Lessa Horta, Joseph Biederman, Luís Augusto Rohde
American Journal of Psychiatry Summary & key facts 2007 5,230 citations

Our findings suggest that geographic location plays a limited role in the reasons for the large variability of ADHD/HD prevalence estimates worldwide. Instead, this variability seems to be explained primarily by the methodological characteristics of studies.

Attention Deficit Hyperactivity Disorder Cognitive Abilities and Testing

The World Health Organization Adult ADHD Self-Report Scale (ASRS): a short screening scale for use in the general population

Ronald C. Kessler, Lenard A. Adler, Minnie Ames, Olga Demler, Stephen V. Faraone, Eva Hiripi, et al.
PubMed Summary & key facts 2005 3,245 citations

The WHO Adult ADHD Self-Report Scale (ASRS) has 18 questions about recent ADHD symptoms, and a shorter six-question screener was tested against blind clinical diagnoses in 154 people from the US National Comorbidity Survey Replication. Each ASRS item was linked to the clinical rating, but agreement varied a lot across…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

The Prevalence and Correlates of Adult ADHD in the United States: Results From the National Comorbidity Survey Replication

Ronald C. Kessler
American Journal of Psychiatry Summary & key facts 2006 2,956 citations

This U.S. study used a nationally representative household survey of 3,199 adults aged 18–44, plus clinical follow-up interviews, to measure adult ADHD. Researchers estimated that 4.4% of adults had current ADHD. Adult ADHD was more common in men, people who were previously married, those who were unemployed, and non-Hispanic white…

Attention Deficit Hyperactivity Disorder Child and Adolescent Psychosocial and Emotional Development Functional Brain Connectivity Studies

Emotion Dysregulation in Attention Deficit Hyperactivity Disorder

Philip Shaw, Argyris Stringaris, Joel T. Nigg, Ellen Leibenluft
American Journal of Psychiatry Summary & key facts 2014 1,128 citations

This review looked at research on emotion dysregulation (problems managing emotions) in people with ADHD. It found three main points: emotion dysregulation is common across the lifespan and causes substantial problems; it may come from trouble noticing, recognizing, or paying attention to emotional cues tied to a brain circuit that…

Attention Deficit Hyperactivity Disorder Mind wandering and attention Sleep and related disorders

Adult ADHD and comorbid disorders: clinical implications of a dimensional approach

Martin A. Katzman, Timothy S. Bilkey, Pratap Chokka, Angelo Fallu, Larry J. Klassen
BMC Psychiatry Summary & key facts 2017 648 citations

This review says adult ADHD affects about 2.5% of adults and often occurs with other mental health problems. Adults with ADHD commonly have trouble with attention, memory, planning, self-control, and emotions. The condition is often missed or undertreated, is linked with big personal and social problems, and the evidence on…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies

Functional Impairments in Adults With Self-Reports of Diagnosed ADHD

Joseph Biederman, Stephen V. Faraone, Thomas Spencer, Eric Mick, Michael C. Monuteaux, Megan Aleardi

In a 2003 survey, 500 adults who said a clinician had diagnosed them with ADHD were compared with 501 age- and gender-matched people from a U.S. national sample. Adults reporting ADHD were less likely to finish high school or college, less likely to be employed, had more job changes, and…

Attention Deficit Hyperactivity Disorder

The global prevalence of ADHD in children and adolescents: a systematic review and meta-analysis

Nader Salari, Hooman Ghasemi, Nasrin Abdoli, Adibeh Rahmani, Mohammad Hossain Shiri, Amir Hossein Hashemian, et al.

The authors pooled results from 61 cross-sectional studies to estimate how common ADHD is in children and adolescents worldwide. They found a pooled prevalence of 7.6% (95% CI 6.1–9.4%) in children aged 3–12 (from 96,907 children) and 5.6% (95% CI 4.8–7%) in adolescents aged 12–18. Prevalence estimates varied by age…

Attention Deficit Hyperactivity Disorder Children's Physical and Motor Development

Females with ADHD: An expert consensus statement taking a lifespan approach providing guidance for the identification and treatment of attention-deficit/ hyperactivity disorder in girls and women

Susan Young, Nicoletta Adamo, Bryndís Björk Ásgeirsdóttir, Polly Branney, Michelle Beckett, William Colley, et al.
BMC Psychiatry Summary & key facts 2020 431 citations

This ADDA article explains ADHD masking — when people hide or copy others to appear "normal." Masking can help someone function but often uses a lot of mental and emotional energy. The article says masking can delay diagnosis, cause burnout or mood problems, and may help explain why women are…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research Child and Adolescent Psychosocial and Emotional Development

The history of attention deficit hyperactivity disorder

Klaus W. Lange, Susanne Reichl, Katharina Lange, Lara Tucha, Oliver Tucha

The paper says the modern DSM-IV-TR idea of ADHD is relatively new, but people with symptoms like inattention, restlessness, and impulsivity were described more than 200 years ago. For example, Sir Alexander Crichton in 1798 wrote about children who could not keep their attention on one thing and were easily…

Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Research

Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway

Nora D. Volkow, Gou‐Jen Wang, Jeffrey H. Newcorn, Scott H. Kollins, Timothy Wigal, Frank Telang, et al.
Molecular Psychiatry Summary & key facts 2010 409 citations

Researchers used PET brain scans to compare dopamine reward-system markers in 45 adults with ADHD and 41 adults without ADHD. People with ADHD scored lower on an Achievement scale (a stand-in measure for motivation), and in the ADHD group those lower scores were linked to lower availability of dopamine D2/D3…

Attention Deficit Hyperactivity Disorder Cognitive Abilities and Testing Neural and Behavioral Psychology Studies

Gender effects on Attention-Deficit/Hyperactivity disorder in adults, revisited

Joseph Biederman, Stephen V. Faraone, Michael C. Monuteaux, Marie Bober, Elizabeth Cadogen
Biological Psychiatry Summary & key facts 2004 380 citations

This study reexamined gender differences in adult ADHD by comparing 219 adults with ADHD to 215 control subjects matched for age and gender. The researchers found no evidence that gender changed how ADHD related to other psychiatric disorders. Adults with ADHD showed cognitive deficits and higher rates of major depression,…

Attention Deficit Hyperactivity Disorder Child and Adolescent Psychosocial and Emotional Development Functional Brain Connectivity Studies

Cognitive Neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) and Its Clinical Translation

Katya Rubia
Frontiers in Human Neuroscience Summary & key facts 2018 354 citations

Brain imaging studies (fMRI) show that ADHD is linked to problems in many brain networks that control attention, timing, working memory, motivation, and emotion. There is also evidence that a brain system normally quiet during tasks (the default mode network) does not switch off properly in people with ADHD. Some…

Attention Deficit Hyperactivity Disorder Functional Brain Connectivity Studies Transcranial Magnetic Stimulation Studies
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