Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

3 papers

Cannabinoids in attention-deficit/hyperactivity disorder: A randomised-controlled trial

Ruth Cooper, Emma Williams, Seth Seegobin, Charlotte Tye, Jonna Kuntsi, Philip Asherson
European Neuropsychopharmacology Summary & key facts 2017 165 citations

This small pilot randomized placebo‑controlled trial tested a cannabinoid spray (Sativex) in 30 adults with ADHD. The main test of cognition and activity (QbTest) showed no significant difference between Sativex and placebo in the intention‑to‑treat analysis (Estimate = -0.17, 95% CI -0.40 to 0.07, p = 0.16). Some secondary measures…

Attention Deficit Hyperactivity Disorder Bipolar Disorder and Treatment Cannabis and Cannabinoid Research

Cannabis use and mood disorders: a systematic review

Maryam Sorkhou, Eliza L Dent, Tony P. George
Frontiers in Public Health Summary & key facts 2024 35 citations

This systematic review looked at studies up to November 2023 on cannabis use and mood disorders. The authors included 78 studies and found that cannabis use was generally linked with more depressive and manic symptoms, a higher chance of developing major depressive disorder (MDD) and bipolar disorder (BD), and a…

Bipolar Disorder and Treatment Cannabis and Cannabinoid Research Child and Adolescent Psychosocial and Emotional Development

Attention Deficit Hyperactivity Disorder, Cannabis Use, and the Endocannabinoid System: A Scoping Review

Jennie E. Ryan, Mitchell Fruchtman, Andrea Sparr‐Jaswa, Amy Knehans, Brooke Worster
Developmental Psychobiology Summary & key facts 2024 7 citations

This scoping review looks at studies about the brain’s endocannabinoid system (ECS) and attention deficit hyperactivity disorder (ADHD). It says lab and clinical work show links between how the ECS works and the thinking or attention problems in ADHD. The review also notes that people with ADHD use cannabis and…

Attention Deficit Hyperactivity Disorder Bipolar Disorder and Treatment Cannabis and Cannabinoid Research
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