Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

4 papers

Antidepressant-associated sexual dysfunction: impact, effects, and treatment

Agnès Higgins

This review says sexual problems are common side effects of many antidepressant medicines. The exact chance varies a lot between studies. Problems can include lower sex drive, less excitement, delayed or lost orgasms, and erection or ejaculation trouble. Some drugs (many SSRIs and venlafaxine) often show high rates, while others…

Hormonal and reproductive studies Sexual function and dysfunction studies Treatment of Major Depression

From Exclusion to Acceptance: Independent Living on the Autistic Spectrum

Martijn Dekker
www.autism.org.uk Summary & key facts 2019 26 citations

The neurodiversity movement grew out of autistic self-advocacy groups in the mid-1990s that met online. It is a social justice movement that asks for civil rights, equality, respect and inclusion for neurodivergent people. Early email lists and forums such as ANI-L (1994) and InLv (founded 1996) helped shape the idea…

Electroconvulsive Therapy Studies Obsessive-Compulsive Spectrum Disorders Treatment of Major Depression

Atypical depression.

Tanvir Singh, Kristi Williams
PubMed 2006 18 citations

Atypical depression is a recognized subtype of depressive illness in the DSM-IV. It often starts early, lasts a long time, and is common in clinic samples. The DSM-IV diagnosis requires mood reactivity plus at least two of: increased appetite, increased sleep, heavy limbs (“leaden paralysis”), or long-standing sensitivity to rejection.…

Bipolar Disorder and Treatment Personality Disorders and Psychopathology Treatment of Major Depression

Does Bupropion Impact More than Mood? A Case Report and Review of the Literature

Waqas Yasin, Syed Ijlal Ahmed, Robert V Gouthro
Cureus Summary & key facts 2019 9 citations

This article describes one patient who developed increased sexual urges after bupropion was added to his ongoing fluoxetine treatment. The urges dropped after bupropion was stopped and replaced with mirtazapine. The authors review other studies showing bupropion usually causes fewer sexual problems than SSRIs but can sometimes raise libido, and…

Neuroendocrine regulation and behavior Sexual function and dysfunction studies Treatment of Major Depression
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