Frontier mental health research: psychedelics & drug studies

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5 papers

A Hypothesis of Gender Differences in Self-Reporting Symptom of Depression: Implications to Solve Under-Diagnosis and Under-Treatment of Depression in Males

Peixia Shi, Aigang Yang, Qing Zhao, Zhaohua Chen, Xiaomei Ren, Qin Dai
Frontiers in Psychiatry Summary & key facts 2021 206 citations

This article proposes a new hypothesis: women report mild-to-moderate depression more often, while men report more severe depression and more suicide. The authors point to possible reasons such as hormone links, men’s tendency to hide feelings or avoid help, and different symptom patterns in men. They say this could mean…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Treatment and Access

Post-Psychedelic Reductions in Experiential Avoidance Are Associated With Decreases in Depression Severity and Suicidal Ideation

Richard J. Zeifman, Anne Catherine Wagner, Ros Watts, Hannes Kettner, Lea J. Mertens, Robin Carhart‐Harris
Frontiers in Psychiatry Summary & key facts 2020 101 citations

Researchers followed two groups of people who planned to use a psychedelic. They gave questionnaires before the trip, then about two weeks and four weeks after. On average, people reported less avoidance of painful thoughts and feelings, lower depression scores, and less thinking about suicide after using a psychedelic. The…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies Other

Therapeutic use of psilocybin: Practical considerations for dosing and administration

Caroline A. MacCallum, Lindsay A. Lo, Carly A. Pistawka, Jagpaul Kaur Deol
Frontiers in Psychiatry Summary & key facts 2022 84 citations

This article gives health care professionals a plain overview of psilocybin-assisted psychotherapy. It summarizes how psilocybin and its active form psilocin work in the brain, how the body absorbs and clears them, practical issues for dosing and monitoring, legal and access changes, and safety concerns for medically complex patients. The…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Psychedelic Mushrooms in the USA: Knowledge, Patterns of Use, and Association With Health Outcomes

Richard Matzopoulos, Robert Morlock, Amy Morlock, Bernard Lerer, Leonard Lerer
Frontiers in Psychiatry Summary & key facts 2022 41 citations

Researchers ran a national online survey of U.S. adults from November 2020 to March 2021 that was weighted to represent the adult population. They asked about use of psychedelic mushrooms (psilocybin), reasons for use, and mental health. Many users said they took mushrooms for general mental health and well-being. Users…

Biochemical Analysis and Sensing Techniques Chemical synthesis and alkaloids Psychedelics and Drug Studies Psilocybin

Factors Related to the Level of Depression and Suicidal Behavior Among Men With Diagnosed Depression, Physically Ill Men, and Healthy Men

Aleksandra Kielan, Mariusz Jaworski, Anna Mosiołek, Jan Chodkiewicz, Łukasz Święcicki, Bożena Walewska‐Zielecka
Frontiers in Psychiatry Summary & key facts 2021 11 citations

This study looked at 598 men in three groups: men diagnosed with depression, men with physical illnesses, and healthy men. The researchers used several questionnaires to find which factors were linked with the level of depressive symptoms and suicidal behavior in each group. They reported different sets of factors for…

Child and Adolescent Psychosocial and Emotional Development Mental Health Treatment and Access Suicide and Self-Harm Studies
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