Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Pharmacotherapy of Anxiety Disorders: Current and Emerging Treatment Options

Amir Garakani, James W. Murrough, Rafael C. Freire, Robyn P. Thom, Kaitlyn Larkin, Frank D. Buono, et al.
Frontiers in Psychiatry Summary & key facts 2020 395 citations

This review summarizes drug treatments for adult anxiety disorders (panic disorder, generalized anxiety disorder, social anxiety disorder, and specific phobias). It says well-known drugs such as SSRIs and SNRIs are commonly used and approved for some anxiety disorders. The authors found that research into truly new medications is limited, many…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Pharmacological Receptor Mechanisms and Effects Tryptophan and brain disorders

A Hypothesis of Gender Differences in Self-Reporting Symptom of Depression: Implications to Solve Under-Diagnosis and Under-Treatment of Depression in Males

Peixia Shi, Aigang Yang, Qing Zhao, Zhaohua Chen, Xiaomei Ren, Qin Dai
Frontiers in Psychiatry Summary & key facts 2021 206 citations

This article proposes a new hypothesis: women report mild-to-moderate depression more often, while men report more severe depression and more suicide. The authors point to possible reasons such as hormone links, men’s tendency to hide feelings or avoid help, and different symptom patterns in men. They say this could mean…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Child and Adolescent Psychosocial and Emotional Development Mental Health Treatment and Access

Trait mindfulness and personality characteristics in a microdosing ADHD sample: a naturalistic prospective survey study

Haijen, Eline C. H. M., Hurks, Petra P. M., Kuypers, Kim P. C.
www.frontiersin.org Summary & key facts 2023 5 citations

This naturalistic survey followed adults with ADHD or severe ADHD symptoms who planned to start psychedelic microdosing. After 4 weeks, participants reported higher overall trait mindfulness — driven by better ability to describe inner experience and to be non-judging — and lower neuroticism, while other Big Five traits did not…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Mindfulness and Compassion Interventions Psychedelics and Drug Studies
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.