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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Digital Mental Health Interventions Psychology The Journal of Clinical Psychiatry

1 paper

Results From a Long-Term Observational Follow-Up Study of a Single Dose of Psilocybin for a Treatment-Resistant Episode of Major Depressive Disorder

Guy M. Goodwin, Anna Nowakowska, Merve Atli, Boadie W. Dunlop, David Feifel, David J. Hellerstein, et al.
The Journal of Clinical Psychiatry Summary & key facts 2025 7 citations

Researchers followed people with treatment-resistant major depressive disorder for 52 weeks after a single dose of a pharmaceutical psilocybin (COMP360). In the original randomized trial (COMP001, n=233), the median time until a prespecified depressive event was 92 days for the 25 mg group, 83 days for the 10 mg group,…

Chemical synthesis and alkaloids Digital Mental Health Interventions Psychedelics and Drug Studies
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