Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

5 papers

Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

Kathleen Kara Fitzpatrick, Alison Darcy, Molly Vierhile
JMIR Mental Health Summary & key facts 2017 2,318 citations

This small randomized trial tested a fully automated text-based conversational agent called Woebot as a way to deliver cognitive behavioral therapy to college-age young adults with symptoms of depression and anxiety. Over 2 weeks, the Woebot group (n=34) showed a statistically larger drop in depression scores (PHQ-9) than an information-only…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Efficacy of digital cognitive behavioral therapy for moderate‐to‐severe symptoms of generalized anxiety disorder: A randomized controlled trial

Jenna R. Carl, Christopher B. Miller, Alasdair L. Henry, Michelle L. Davis, Richard Stott, Jasper A. J. Smits, et al.
Depression and Anxiety Summary & key facts 2020 80 citations

Digital CBT (Daylight) appears to be safe and efficacious for symptoms of anxiety, worry, and further measures of mental health compared with waitlist control in individuals with GAD.

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Digital Mental Health Interventions Mental Health Research Topics

Effectiveness of Digital Mental Health Tools to Reduce Depressive and Anxiety Symptoms in Low- and Middle-Income Countries: Systematic Review and Meta-analysis

Jiyeong Kim, Lois Maame Donkor Aryee, Heejung Bang, Steffi Prajogo, Yong Kyung Choi, Jeffrey S. Hoch, et al.
JMIR Mental Health Summary & key facts 2023 63 citations

The researchers did a large, careful search for studies of digital mental health tools (things like websites, phone apps, text messages, or online therapy) aimed at reducing depression and anxiety in low- and middle-income countries. They only kept randomized controlled trials, which are studies where people are randomly put into…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Internet-Delivered Versus Face-to-Face Cognitive Behavior Therapy for Anxiety Disorders: Systematic Review and Meta-Analysis

Narges Esfandiari, Mohammad A Mazaheri, Saeed Akbari-Zardkhaneh, Vahid Sadeghi-Firoozabadi, Mona Cheraghi
PubMed Central (PMC) Summary & key facts 2021 41 citations

This review pooled data from trials that directly compared therapist-guided internet-delivered CBT (ICBT) with face-to-face CBT for anxiety disorders. Eight randomized studies were included, and the combined result showed a near-zero difference between the two formats (Hedges' g = 0.01, 95% CI −0.16 to 0.18). The authors concluded that ICBT…

Digital Mental Health Interventions Impact of Technology on Adolescents Mental Health Research Topics

Aggression as successful self‐control

David S. Chester

This paper challenges the common idea that aggression only happens when self-control fails. It reviews many studies that show aggression can also result from successful self-control. The author explains how theories of aggression could be changed to include both cases, and says this opens new research questions. The paper also…

Behavioral Health and Interventions Death Anxiety and Social Exclusion Mental Health Research Topics
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