Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

3 papers

More treatment but no less depression: The treatment-prevalence paradox

Johan Ormel, Steven D. Hollon, Ronald C. Kessler, Pim Cuijpers, Scott M. Monroe
PubMed Summary & key facts 2022 188 citations

Treatments for depression have gotten better and far more people can get them since the 1980s. Yet the share of people in the general population with depression has not gone down. The authors call this the “treatment-prevalence paradox” and review seven possible explanations. They find little evidence that more cases…

Mental Health Research Topics Mental Health Treatment and Access Treatment of Major Depression

Depression and eating disorders: Treatment and course

David Mischoulon, Kamryn T. Eddy, Aparna Keshaviah, Diana Dinescu, Stephanie L. Ross, Andrea E. Kass, et al.
Journal of Affective Disorders Summary & key facts 2010 137 citations

This long study followed 246 treatment-seeking women with anorexia or bulimia for about 9 years. Major depression was common and often long-lasting: 70% of those who had depression recovered, but 65% of those who recovered later relapsed. Recovery chances varied by type of eating disorder, and time on antidepressants was…

Eating Disorders and Behaviors Mental Health Research Topics Treatment of Major Depression

Talking sensibly about depression

Vikram Patel
PLoS Medicine Summary & key facts 2017 78 citations

This essay argues that depression symptoms lie on a continuum from wellness to distress to disorder. The author proposes a staged model so people with different levels of symptoms can get different kinds of help. He reviews evidence that most people who meet a binary diagnosis have mild or moderate…

Mental Health Research Topics Mental Health Treatment and Access Treatment of Major Depression
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