Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

3 papers

Neurophysiological activity following rewards and losses among female adolescents and young adults with borderline personality disorder.

Jeremy G. Stewart, Paris Singleton, Erik M. Benau, Dan Foti, Hannah Allchurch, Cynthia S. Kaplan, et al.
Journal of Abnormal Psychology Summary & key facts 2019 16 citations

This study recorded brain activity (EEG) while 68 females aged 13–23 (35 with borderline personality disorder, 33 healthy) did a guessing task with equal wins and losses. People with BPD showed less difference in their brain responses to wins versus losses than healthy peers. Time-frequency tests suggested this smaller difference…

Attention Deficit Hyperactivity Disorder Mental Health Research Topics Personality Disorders and Psychopathology

The relationship between individuals with fearful-avoidant adult attachment orientation and early neural responses to emotional content: An event-related potentials (ERPs) study.

Orrie Dan, Ghadir Zreik, Sivan Raz
Neuropsychology Summary & key facts 2019 16 citations

The study measured very early brain responses to emotional and neutral pictures in 119 undergraduate students (91 female, mean age 23.5 ± 3.6). It compared 30 fearful-avoidant people with 32 secure, 28 anxious-preoccupied, and 29 dismissive-avoidant participants. Fearful-avoidant individuals showed patterns in the early ERP components P1 (110–165 ms) and…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Attachment and Relationship Dynamics Attention Deficit Hyperactivity Disorder

Safety and Efficacy of Repeated Low-Dose LSD for ADHD Treatment in Adults

Lorenz Mueller, Joyce Santos de Jesus, Yasmin Schmid, Felix Müller, A. Becker, Aaron Klaiber, et al.
JAMA Psychiatry Summary & key facts 2025 7 citations

This was a 6-week, double-blind, placebo-controlled trial that tested low-dose LSD (20 μg) given twice weekly in 53 adults with moderate to severe ADHD. Both the LSD group and the placebo group showed similar symptom reductions by week 6 (LSD mean change on the ADHD rating scale −7.1 points; placebo…

Attention Deficit Hyperactivity Disorder Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.