Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

30 papers

Effects of mindfulness on psychological health: A review of empirical studies

Shian‐Ling Keng, Moria J. Smoski, Clive J. Robins
Clinical Psychology Review Summary & key facts 2011 2,599 citations

This 2011 review looked at many studies on mindfulness and mental health. It defines mindfulness as paying attention in the present with nonjudgmental acceptance and says this involves both focusing attention and an open, curious attitude. The authors examined three kinds of research—correlational studies, intervention trials, and lab experiments—and concluded…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Mindfulness and Compassion Interventions Religion, Spirituality, and Psychology

Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis

Alberto Chiesa, Alessandro Serretti

MBSR is able to reduce stress levels in healthy people. However, important limitations of the included studies as well as the paucity of evidence about possible specific effects of MBSR in comparison to other nonspecific treatments underline the necessity of further research.

COVID-19 and Mental Health Mindfulness and Compassion Interventions Resilience and Mental Health

Self-Compassion: Theory, Method, Research, and Intervention

Kristin D. Neff
PubMed Summary & key facts 2023 721 citations

This review defines self-compassion as being supportive toward yourself during suffering and presents a six-part model (more self-kindness and common humanity and mindfulness; less self-judgment, isolation, and overidentification). It summarizes a growing set of empirical studies that suggest self-compassion helps people handle distressing thoughts and emotions and is linked to…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes COVID-19 and Mental Health Mindfulness and Compassion Interventions

Mindfulness-Based Interventions for Anxiety and Depression

Stefan G Hofmann, Angelina F Gómez
PubMed Central (PMC) Summary & key facts 2017 706 citations

Mindfulness-based interventions (MBIs), especially Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT), teach people to pay nonjudgmental attention to the present moment. Reviews and randomized trials show MBIs can reduce anxiety and depression symptom severity across many groups, often doing better than non-evidence treatments or active controls and performing…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes COVID-19 and Mental Health Mindfulness and Compassion Interventions

A Randomized Controlled Effectiveness Trial of Acceptance and Commitment Therapy and Cognitive Therapy for Anxiety and Depression

Evan M. Forman, James D. Herbert, Ethan Moitra, Peter D. Yeomans, Pamela A. Geller
Behavior Modification Summary & key facts 2007 682 citations

The source explains what Acceptance and Commitment Therapy (ACT) is and reports research comparing ACT with cognitive therapy (CT). In a randomized trial of 101 outpatients with moderate to severe anxiety or depression, people assigned to ACT or to CT showed large, similar improvements in depression, anxiety, daily functioning, quality…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Complementary and Alternative Medicine Studies Mindfulness and Compassion Interventions

Brief structured respiration practices enhance mood and reduce physiological arousal

Melis Yilmaz Balban, Eric Neri, Manuela M. Kogon, Lara Weed, Bita Nouriani, Booil Jo, et al.
Summary & key facts 226 citations

In a remote, randomized trial (NCT05304000), people did one of three five-minute daily breathing exercises or five minutes of mindfulness meditation each day for one month. The researchers measured mood, anxiety, and physiological arousal (breathing rate, heart rate, and heart rate variability). Breathwork—especially exhale-focused cyclic sighing—produced bigger mood gains and…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes COVID-19 and Mental Health Mindfulness and Compassion Interventions

Meditation and yoga for posttraumatic stress disorder: A meta-analytic review of randomized controlled trials

Autumn M. Gallegos, Hugh F. Crean, Wilfred R. Pigeon, Kathi L. Heffner
Clinical Psychology Review Summary & key facts 2017 178 citations

This paper pooled results from 19 randomized trials with 1,173 adults to see if meditation and yoga change PTSD symptoms. Overall, these mind–body practices were linked to a small-to-medium reduction in PTSD symptoms (effect size = −0.39). The authors found no big differences by type of practice, who was studied,…

Mindfulness and Compassion Interventions Posttraumatic Stress Disorder Research Resilience and Mental Health

Breathing‐Based Meditation Decreases Posttraumatic Stress Disorder Symptoms in U.S. Military Veterans: A Randomized Controlled Longitudinal Study

Emma Seppälä, Jack B. Nitschke, Dana Tudorascu, Andrea S Hayes, Michael R. Goldstein, Dong T. H. Nguyen, et al.
Journal of Traumatic Stress Summary & key facts 2014 177 citations

This randomized study tested a breathing-based meditation (Sudarshan Kriya yoga) in 21 male U.S. veterans of the Iraq or Afghanistan wars. Participants were randomly assigned to the meditation group (n = 11) or a waitlist control (n = 10). The meditation group showed reductions in self-reported PTSD symptoms, anxiety, and…

Mindfulness and Compassion Interventions Posttraumatic Stress Disorder Research Stress Responses and Cortisol

Regional Brain Activation during Meditation Shows Time and Practice Effects: An Exploratory FMRI Study

E. Baron Short, Samet Köse, Qiwen Mu, Jeffery J. Borckardt, Andrew B. Newberg, Mark S. George, et al.

Meditation involves attentional regulation and may lead to increased activity in brain regions associated with attention such as dorsal lateral prefrontal cortex (DLPFC) and anterior cingulate cortex (ACC). Using functional magnetic resonance imaging, we examined whether DLPFC and ACC were activated during meditation. Subjects who meditate were recruited and scanned…

EEG and Brain-Computer Interfaces Mindfulness and Compassion Interventions Neural and Behavioral Psychology Studies

Developing Self-Awareness: Learning Processes for Self- and Interpersonal Growth

Manuel London, Valerie I. Sessa, Loren A. Shelley

This open-access review article (Jan 2023) looks at what self-awareness is, how it develops, and how researchers measure it. The authors summarize evidence on both benefits and costs (including the downsides of too much inward focus), offer a framework that links learning processes, and report a literature search showing educational…

Job Satisfaction and Organizational Behavior Mindfulness and Compassion Interventions Motivation and Self-Concept in Sports

Mindful awareness in body-oriented therapy as an adjunct to women’s substance use disorder treatment: a pilot feasibility study

Cynthia Price, Elizabeth A. Wells, Dennis M. Donovan, Tessa Rue
PubMed Summary & key facts 2012 90 citations

This small randomized pilot study tested a therapy called Mindful Awareness in Body-Oriented Therapy (MABT) as an extra treatment for women in substance use disorder (SUD) care. Forty-six women were enrolled and those in the MABT group received eight weekly one-on-one sessions in addition to usual care. At the main…

Eating Disorders and Behaviors Mindfulness and Compassion Interventions Psychosomatic Disorders and Their Treatments

Mindful walking in psychologically distressed individuals: a randomized controlled trial

Michael Teut, E. J. Roesner, Miriam Ortiz, Frauke Reese, Sylvia Binting, Stephanie Roll, et al.
PubMed Summary & key facts 2013 50 citations

This randomized trial put 74 adults with moderate-to-high perceived stress into either an 8-session mindful walking program over 4 weeks or a waiting-list control. After 4 weeks, the mindful walking group had a much larger drop in perceived stress scores than the control group. The study also reported better quality-of-life…

Art Therapy and Mental Health Mindfulness and Compassion Interventions Psychosomatic Disorders and Their Treatments
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.