Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

3 papers

More treatment but no less depression: The treatment-prevalence paradox

Johan Ormel, Steven D. Hollon, Ronald C. Kessler, Pim Cuijpers, Scott M. Monroe
PubMed Summary & key facts 2022 188 citations

Treatments for depression have gotten better and far more people can get them since the 1980s. Yet the share of people in the general population with depression has not gone down. The authors call this the “treatment-prevalence paradox” and review seven possible explanations. They find little evidence that more cases…

Mental Health Research Topics Mental Health Treatment and Access Treatment of Major Depression

Clinical and subthreshold panic disorder

Alexander Bystritsky, Lauren Kerwin, Noosha Niv, Jaime L. Natoli, Natalie Abrahami, Ruth Klap, et al.
Depression and Anxiety Summary & key facts 2009 60 citations

This study reports that both full panic disorder (PD) and milder, “subthreshold” panic are linked with other mental health problems, trouble at work, and high use of health services. The authors used data from a large U.S. household survey to compare people with PD and varying levels of panic symptoms.…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Mental Health Research Topics Mental Health Treatment and Access

Symptom Overlap Between Depression and Borderline Personality Disorder: A Network Analysis

Bess M. Kew, Nathan J Monk, Tamlin S. Conner, Chris Frampton, Roger Mulder, Richard Porter, et al.

Researchers combined baseline data from 548 people in four clinical trials who all had current major depression. They used a network analysis, a method that maps how symptoms link to each other, to see which borderline personality disorder (BPD) and depression symptoms connect. After accounting for how severe the depression…

Bipolar Disorder and Treatment Mental Health Research Topics Schizophrenia research and treatment
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