Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

15 papers

Sleep timing, sleep consistency, and health in adults: a systematic review

Jean‐Philippe Chaput, Caroline Dutil, Ryan B. Featherstone, Robert Ross, Lora Giangregorio, Travis J. Saunders, et al.

This review looked at 41 studies with 92,340 adults to see how sleep timing and day-to-day regularity relate to health. It found that going to bed or waking up later, and having more variable sleep patterns, were generally linked to worse health. Social jetlag was linked to worse health, while…

Sleep and related disorders Sleep and Wakefulness Research Sleep and Work-Related Fatigue

Youth Screen Media Habits and Sleep

Lauren Hale, Gregory W. Kirschen, Monique K. LeBourgeois, Michael Gradisar, Michelle M. Garrison, Hawley E. Montgomery‐Downs, et al.

Many children and teens do not get enough sleep. Studies link use of screens, especially in the bedroom or in the hour before bed, to later bedtimes and less total sleep. Experts have set sleep-hour ranges for each age. Research also links short or disrupted sleep to emotional, behavioral, and…

Child Development and Digital Technology Sleep and related disorders Sleep and Wakefulness Research

The effects of physical activity on cortisol and sleep: A systematic review and meta-analysis

Len De Nys, Kerry Anderson, Esther Frema Ofosu, Gemma C. Ryde, Jenni Connelly, Anna C. Whittaker
Psychoneuroendocrinology Summary & key facts 2022 227 citations

This review combined results from 10 intervention studies to see if physical activity programs change cortisol (a stress hormone) and sleep in adults. The pooled results found lower cortisol after activity programs and some improvement in sleep quality. The authors say the evidence is moderate for cortisol and low for…

Circadian rhythm and melatonin Physical Activity and Health Sleep and related disorders

Effects of Singing Bowl Sound Meditation on Mood, Tension, and Well-being: An Observational Study

Tamara L. Goldsby, Michael E. Goldsby, Mary McWalters, Paul J. Mills

This observational study tested Tibetan singing bowl sound meditation with 62 adults (mean age 49.7). After the session, people reported less tension, anger, fatigue, and depressed mood, and higher spiritual well-being. People who had never tried this meditation before showed a larger drop in tension than people who had experience.…

Music Therapy and Health Neuroscience and Music Perception Sleep and related disorders

The impact of exercise on depression: how moving makes your brain and body feel better

Md Najmul Hossain, Jaeeun Lee, Hongseok Choi, Yi-Sub Kwak, Jongnam Kim
www.e-pan.org Summary & key facts 2024 75 citations

This review of research up to October 2023 explains many ways exercise may help people with depression. The authors describe biological changes (for example, more endorphins, less inflammation, and higher levels of brain-supporting molecules like BDNF), plus psychological and behavioral benefits (better sleep, less rumination, more self‑esteem and social contact).…

Psychological Well-being and Life Satisfaction Sleep and related disorders Tryptophan and brain disorders

Cannabis use and sleep: Expectations, outcomes, and the role of age

Evan A. Winiger, Leah N. Hitchcock, Angela D. Bryan, L. Cinnamon Bidwell
Addictive Behaviors Summary & key facts 2020 63 citations

This study looked at 152 moderate cannabis users (21–70 years old) to see what they expect cannabis will do for sleep and what their reported sleep was like. Users were more likely to expect cannabis to help sleep, but the study found few clear links between cannabis use and better…

Cannabis and Cannabinoid Research Sleep and related disorders Sleep and Wakefulness Research

Neurobiological Changes Induced by Mindfulness and Meditation: A Systematic Review

Andrea Calderone, Dèsiréè Latella, Federica Impellizzeri, Paolo De Pasquale, Fausto Famà, Angelo Quartarone, et al.
Biomedicines Summary & key facts 2024 49 citations

This systematic review of research up to 2024 found that meditation and mindfulness are linked to measurable brain changes and to better emotional regulation, cognition, and stress resilience. Many studies report thicker cortex in certain areas, lower amygdala reactivity, changes in brain connectivity and neurotransmitters, and improvements in anxiety, depression,…

Mindfulness and Compassion Interventions Music Therapy and Health Sleep and related disorders

Interventions for Sleep Disturbance in Bipolar Disorder

Allison G Harvey, Kate A Kaplan, Adriane Soehner
PubMed Central (PMC) Summary & key facts 2015 45 citations

This review explains that sleep problems are common in bipolar disorder and are tied to worse mood, more relapse, and more daily problems. The authors describe non-drug treatments for sleep, especially adapted cognitive behavioral therapy for insomnia (CBT-I), and note some evidence and limits for these approaches.

Bipolar Disorder and Treatment Sleep and related disorders Sleep and Wakefulness Research

Differential Experimental Effects of a Short Bout of Walking, Meditation, or Combination of Walking and Meditation on State Anxiety Among Young Adults

Meghan K. Edwards, Simon Rosenbaum, Paul D. Loprinzi

This randomized trial tested whether a single short bout of walking, meditation, or a combination changed short-term anxiety in young adults. One hundred ten university students (mean age 21.4 years) were randomly assigned to 10 minutes of walking, 10 minutes of meditation, walking then meditation, meditation then walking, or sitting.…

Mindfulness and Compassion Interventions Sleep and related disorders Urban Green Space and Health

Sleep and Alcohol Use Patterns During Federal Holidays and Daylight Saving Time Transitions in the United States

Heacock, Rachel M., Capodilupo, Emily R., Czeisler, Mark É., et al.
www.frontiersin.org Summary & key facts 2022 25 citations

This study used data from 24,250 U.S. users of the WHOOP wearable (74.5% male, mean age 37.6 years) collected from May 1, 2020 to May 1, 2021. Compared to typical days, most U.S. public holidays, holiday eves, and Daylight Saving Time transitions showed clear changes: people tended to sleep longer,…

Impact of Light on Environment and Health Sleep and related disorders Sleep and Work-Related Fatigue

Cannabis use in patients with insomnia and sleep disorders: Retrospective chart review

Régis Vaillancourt, Shannon Gallagher, Jameason D. Cameron, Rahim Dhalla

This small, retrospective chart review looked at patients who used medical cannabis for insomnia at a community pharmacy in Ottawa. Of 38 patients with enough follow-up, 27 (71%) said their sleep or related symptoms were better, and 15 (39%) reduced or stopped a prescription sleep medicine. Eight patients (21%) reported…

Cannabis and Cannabinoid Research Sleep and related disorders Sleep and Wakefulness Research

Impact of Himalayan Singing Bowls Meditation Session on Mood and Heart Rate Variability – An Observational Study

Saharsh Panchal, Fariburz Irani, Gunjan Y Trivedi

This small observational study checked mood and heart-rate measures before and after one 40-minute seated Himalayan singing bowl (HSB) sound-bath. After the session, 77 people reported higher positive affect and lower negative affect on the PANAS mood survey. A smaller group (17) filling the POMS survey reported less tension, anger,…

Heart Rate Variability and Autonomic Control Mindfulness and Compassion Interventions Sleep and related disorders
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