Frontier mental health research: psychedelics & drug studies

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2 papers

Cannabis analgesia in chronic neuropathic pain is associated with altered brain connectivity

Libat Weizman, Lior Dayan, Silviu Brill, Hadas Nahman‐Averbuch, Talma Hendler, Giris Jacob, et al.
Neurology Summary & key facts 2018 117 citations

In a small randomized, double-blind crossover study of 15 men with chronic radicular lower‑limb neuropathic pain, a single sublingual dose of THC (about 15.4 mg on average) reduced pain more than placebo. The amount of pain relief was linked to changes on resting‑state fMRI: reduced connectivity between emotional/cognitive brain areas…

Cannabis and Cannabinoid Research Pain Mechanisms and Treatments Psychedelics and Drug Studies Cannabis

Psychedelic therapies reconsidered: compounds, clinical indications, and cautious optimism

Jennifer Mitchell, B. Anderson
Neuropsychopharmacology Summary & key facts 2023 44 citations

This review describes a rapid rise in medical research on psychedelic drugs over the past five years. Several later-stage clinical trials have been published, and many different drugs — including psilocybin, MDMA, ketamine, LSD, ayahuasca, and ibogaine — are being tested for conditions such as depression, post‑traumatic stress, addiction, obsessive‑compulsive…

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies Ayahuasca Ibogaine
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