The Effects of Acutely Administered 3,4-Methylenedioxymethamphetamine on Spontaneous Brain Function in Healthy Volunteers Measured with Arterial Spin Labeling and Blood Oxygen Level–Dependent Resting State Functional Connectivity
In a double-blind, placebo-controlled study, 25 healthy volunteers each took a single 100 mg dose of MDMA or placebo (one week apart) while their brains were scanned. MDMA produced clear increases in positive mood and caused localized decreases in blood flow in parts of the right medial temporal lobe (including…