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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Neurotransmitter Receptor Influence on Behavior Chemistry British Journal of Pharmacology

1 paper

The phytocannabinoid, Δ9‐tetrahydrocannabivarin, can act through 5‐HT1A receptors to produce antipsychotic effects

Maria Grazia Cascio, Erica Zamberletti, Pietro Marini, Daniela Parolaro, Roger G. Pertwee
British Journal of Pharmacology Summary & key facts 2014 62 citations

This study tested the cannabis-related compound THCV in lab and rat experiments. In lab tests on rat brain membranes and human cells, 100 nM THCV increased activation of the serotonin 5-HT1A receptor and changed how a 5-HT1A probe bound to the receptor. In rats treated with phencyclidine (a model for…

Cannabis and Cannabinoid Research Neuroscience and Neuropharmacology Research Neurotransmitter Receptor Influence on Behavior
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.