Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

1 paper

Tetrahydrocannabinolic acid reduces nausea-induced conditioned gaping in rats and vomiting in Suncus murinus

E M Rock, R L Kopstick, C L Limebeer, L A Parker
PubMed Central (PMC) Summary & key facts 2013 62 citations

This study tested tetrahydrocannabinolic acid (THCA) in animal models of nausea and vomiting. In rats, THCA at 0.05 and 0.5 mg·kg−1 reduced LiCl-induced conditioned gaping, a behavior linked to nausea. In the house musk shrew (Suncus murinus), the same THCA doses reduced LiCl-induced vomiting. These effects were reversed by the…

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