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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Mental Health Research Topics Alternative medicine Clinical Psychopharmacology and Neuroscience

1 paper

Current Understanding on Psilocybin for Major Depressive Disorder: A Review Focusing on Clinical Trials

Sheng‐Min Wang, Sunghwan Kim, Won-Seok Choi, Hyun Kook Lim, Young Sup Woo, Chi‐Un Pae, et al.
Clinical Psychopharmacology and Neuroscience Summary & key facts 2023 13 citations

This review looked at published clinical trials of psilocybin for depression. It found 11 trials (six open‑label and five double‑blind randomized trials) that report rapid antidepressant and anti‑anxiety effects in some patients. The paper describes how psilocybin acts on serotonin 5‑HT2A receptors, may boost brain plasticity, and may lower brain…

Mental Health Research Topics Psychedelics and Drug Studies Tryptophan and brain disorders
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.