Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

5 papers

Depression and eating disorders: Treatment and course

David Mischoulon, Kamryn T. Eddy, Aparna Keshaviah, Diana Dinescu, Stephanie L. Ross, Andrea E. Kass, et al.
Journal of Affective Disorders Summary & key facts 2010 137 citations

This long study followed 246 treatment-seeking women with anorexia or bulimia for about 9 years. Major depression was common and often long-lasting: 70% of those who had depression recovered, but 65% of those who recovered later relapsed. Recovery chances varied by type of eating disorder, and time on antidepressants was…

Eating Disorders and Behaviors Mental Health Research Topics Treatment of Major Depression

Effects of aromatherapy on anxiety: A meta-analysis of randomized controlled trials

Minmin Gong, Hui Dong, Yueheng Tang, Wenya Huang, Fuer Lu
PubMed Summary & key facts 2020 115 citations

This meta-analysis combined 32 randomized trials from 25 articles to see if aromatherapy lowers anxiety. It found that both inhalation and massage aromatherapy were linked with lower scores on a common anxiety scale (STAI). The review noted no reported side effects, but said more research is needed on the right…

Olfactory and Sensory Function Studies

Long-term outcomes of repeated ketamine infusions in patients with unipolar and bipolar depression: A naturalistic follow-up study

Weicheng Li, Yanling Zhou, Weijian Liu, Chengyu Wang, Xiaofeng Lan, Zhipei Zhang, et al.
Journal of Affective Disorders Summary & key facts 2021 13 citations

Researchers followed 108 people with unipolar or bipolar depression who had repeated ketamine infusions (three times weekly over 12 days) and then were observed for 9 months. Depression symptoms and overall function were measured with the PHQ‑9 and the GAF. Seventy‑one people (65.7%) completed the full 9‑month follow‑up. At month…

Mental Health Research Topics Treatment of Major Depression Tryptophan and brain disorders

Effects of combining physical activity with psychotherapy on mental health and well-being: A systematic review

PubMed Summary & key facts 2020 0 citations

This systematic review looked at 22 trials (searched up to December 2018) that combined physical activity with psychotherapy to improve mental health and well‑being. Overall, combined programs tended to produce better psychological outcomes than usual care, and many studies found similar benefits from physical activity alone. However, study methods varied…

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