Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

3 papers

Δ9-Tetrahydrocannabivarin (THCV): a commentary on potential therapeutic benefit for the management of obesity and diabetes

Amos Olusegun Abioye, Olubukola Ayodele, Aleksandra Marinkovic, Risha Patidar, Adeola Akinwekomi, Adekunle Sanyaolu
Journal of Cannabis Research Summary & key facts 2020 80 citations

THCV is a cannabis compound that does not cause the “high” linked to THC. In animal studies it lowered appetite, increased feelings of fullness, and raised energy use, and some small studies in people with type 2 diabetes found lower fasting blood sugar versus placebo. Researchers say these findings make…

Cannabis and Cannabinoid Research Diet, Metabolism, and Disease Neurotransmitter Receptor Influence on Behavior

An emerging trend in Novel Psychoactive Substances (NPSs): designer THC

Cristian Caprari, Elena Ferri, Maria Angela Vandelli, Cinzia Citti, Giuseppe Cannazza
PubMed Central (PMC) Summary & key facts 2024 27 citations

This review explains that many THC-like chemicals have been made from Δ9-THC over time. It describes their chemistry, how they are made, how they act in the body, lab testing methods, and reports from users. Some of these compounds occur in tiny amounts in natural cannabis, others are made in…

Cannabis and Cannabinoid Research GABA and Rice Research Psychedelics and Drug Studies

Changes in health-related quality of life over the first three months of medical marijuana use

Michelle R. Lent, Thomas R. McCalmont, Megan M. Short, Karen L. Dugosh
Journal of Cannabis Research Summary & key facts 2024 4 citations

This prospective observational study followed 438 adults who were new medical‑marijuana patients in Pennsylvania. Using the SF‑36 survey, participants reported statistically significant improvements in all eight areas of health‑related quality of life from before starting medical marijuana to three months later (P < .001 for all domains). Older participants showed…

Cannabis and Cannabinoid Research Homelessness and Social Issues Religion, Spirituality, and Psychology
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