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2 papers
This review looks at research on psychedelic drugs, especially psilocybin. It says recent human studies show a single dose can give lasting relief from severe depression, and regulators have given two late-stage psilocybin trials special 'Breakthrough Therapy' status. The paper also pulls together lab and animal studies that suggest psychedelics…
Researchers isolated two compounds from the medicinal mushroom Hericium erinaceus—N-de phenylethyl isohericerin (NDPIH) and hericene A. In lab cultures, these compounds caused strong axon growth and more branching in hippocampal neurons even without serum. Tests showed they activate ERK1/2 signaling and do not act only through the TrkB (BDNF) receptor.…
