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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Brain-derived neurotrophic factor Molecular Psychiatry

1 paper

Effects of psychoplastogens on blood levels of brain-derived neurotrophic factor (BDNF) in humans: a systematic review and meta-analysis

Abigail E. Calder, Adrian Hase, Gregor Hasler
Molecular Psychiatry Summary & key facts 2024 10 citations

Researchers pooled results from 29 human studies that measured blood levels of a protein called brain-derived neurotrophic factor, or BDNF, after people received so-called psychoplastogen drugs such as ketamine or psychedelics. They found no clear change in blood BDNF after these drugs. The authors say this does not prove the…

Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies Treatment of Major Depression Ayahuasca Ketamine
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