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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Anesthesia and Neurotoxicity Research Bioinformatics Psychopharmacology

1 paper

Molecular pathways of ketamine: A systematic review of immediate and sustained effects on PTSD

Nathan J. Wellington, Ana Paula Bouças, Jim Lagopoulos, Bonnie L. Quigley, Anna Kuballa
Psychopharmacology Summary & key facts 2025 12 citations

Researchers reviewed about 300 studies and closely read 29 that tested how ketamine changes the brain at the molecular level in post-traumatic stress disorder (PTSD). They looked at short-term changes that happen while the drug is active and longer-term changes that can last after the drug is gone. Short-term changes…

Anesthesia and Neurotoxicity Research Treatment of Major Depression Tryptophan and brain disorders Ketamine
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.