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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Genetics Psychopharmacology Bulletin

1 paper

Brexanolone to Treat Postpartum Depression in Adult Women

Elyse M. Cornett, Lauren Rando, Austin M Labbé, Wil Perkins, Adam M. Kaye, Alan D. Kaye, et al.
Psychopharmacology Bulletin Summary & key facts 2025 32 citations

Brexanolone (brand name ZULRESSO) is an FDA-approved drug for moderate-to-severe postpartum depression. In trials it reduced depressive symptoms quickly and had mostly mild side effects, but it is given by IV in a monitored inpatient setting because it can cause heavy sleepiness and even loss of consciousness. It is not…

Maternal Mental Health During Pregnancy and Postpartum Neuroendocrine regulation and behavior Stress Responses and Cortisol
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.