Frontier mental health research: psychedelics & drug studies

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2 papers

Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers

Joseph M. Rootman, Pamela Kryskow, Kalin Harvey, Paul Stamets, Eesmyal Santos-Brault, Kim P. C. Kuypers, et al.
Scientific Reports Summary & key facts 2021 75 citations

This study used a smartphone app to compare 4,050 people who said they microdose psychedelics with 4,653 people who did not. Psilocybin was the most common microdose substance, and people who microdosed often said they did so for health and wellness reasons. In people who reported past mental health concerns,…

Biochemical Analysis and Sensing Techniques Chemical synthesis and alkaloids Psychedelics and Drug Studies

Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls

Joseph M. Rootman, Maggie Kiraga, Pamela Kryskow, Kalin Harvey, Paul Stamets, Eesmyal Santos-Brault, et al.
Scientific Reports Summary & key facts 2022 49 citations

Researchers followed 953 people who microdosed psilocybin and 180 non-microdosing controls for about 30 days. Microdosers showed small-to-medium improvements in mood and overall mental health at one month compared with controls. These improvements were seen across genders, age groups, and in people with and without prior mental health concerns. The…

Chemical synthesis and alkaloids Complementary and Alternative Medicine Studies Psychedelics and Drug Studies
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