Menu
Start Screening

Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Magnetic resonance imaging Translational Psychiatry

2 papers

Rapid neuroplasticity changes and response to intravenous ketamine: a randomized controlled trial in treatment-resistant depression

Jared M. Kopelman, Timothy A. Keller, Benjamin Panny, Angela Griffo, Michelle Degutis, Crystal Spotts, et al.
Translational Psychiatry Summary & key facts 2023 52 citations

In a randomized trial, 98 adults with treatment-resistant depression had brain scans before and 24 hours after a single intravenous infusion of ketamine (0.5 mg/kg) or saline. The researchers measured mean diffusivity (DTI-MD), an MRI-based, indirect marker of microstructural brain change that tends to fall when new synapses or tissue…

Advanced MRI Techniques and Applications Functional Brain Connectivity Studies Treatment of Major Depression

The diagnosis of ASD with MRI: a systematic review and meta-analysis

Sjir J. C. Schielen, Jesper Pilmeyer, Albert P. Aldenkamp, Svitlana Zinger
Translational Psychiatry Summary & key facts 2024 15 citations

This review combined 134 studies (159 experiments) that tried to tell apart people with autism spectrum disorder (ASD) from healthy controls using resting-state MRI. Across studies the pooled accuracy was moderate: about 76% sensitivity, 75.7% specificity, and an AUC of 0.823. However, the authors say there is a lot of…

Autism Spectrum Disorder Research Child Development and Digital Technology Genetics and Neurodevelopmental Disorders
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.