Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

2 papers

Ayahuasca: A review of historical, pharmacological, and therapeutic aspects

Simon Ruffell, Max Crosland‐Wood, Rob Palmer, Nige Netzband, WaiFung Tsang, Brandon Weiss, et al.

This paper is a clear review of ayahuasca, the Amazon plant brew made from the Banisteriopsis caapi vine plus a DMT-containing plant such as Psychotria viridis. The authors summarize its history, how it acts in the body and brain, what people report feeling during the experience, and the early research…

Biochemical Analysis and Sensing Techniques Natural Compound Pharmacology Studies Psychedelics and Drug Studies Ayahuasca

The potential of 5‐methoxy‐N,N‐dimethyltryptamine in the treatment of alcohol use disorder: A first look at therapeutic mechanisms of action

Stephan Tap
Addiction Biology Summary & key facts 2024 11 citations

This paper is a first look at whether the fast-acting psychedelic 5‑MeO‑DMT might help people with alcohol use disorder. The authors reviewed existing studies in humans and animals and found early signs that 5‑MeO‑DMT can cause intense mystical feelings and a loss of self-boundaries, and that it changes brain rhythms…

Cannabis and Cannabinoid Research Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies LSD Other
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