Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

3 papers

Cannabinoids in attention-deficit/hyperactivity disorder: A randomised-controlled trial

Ruth Cooper, Emma Williams, Seth Seegobin, Charlotte Tye, Jonna Kuntsi, Philip Asherson
European Neuropsychopharmacology Summary & key facts 2017 165 citations

This small pilot randomized placebo‑controlled trial tested a cannabinoid spray (Sativex) in 30 adults with ADHD. The main test of cognition and activity (QbTest) showed no significant difference between Sativex and placebo in the intention‑to‑treat analysis (Estimate = -0.17, 95% CI -0.40 to 0.07, p = 0.16). Some secondary measures…

Attention Deficit Hyperactivity Disorder Bipolar Disorder and Treatment Cannabis and Cannabinoid Research

Safety and Efficacy of Repeated Low-Dose LSD for ADHD Treatment in Adults

Lorenz Mueller, Joyce Santos de Jesus, Yasmin Schmid, Felix Müller, A. Becker, Aaron Klaiber, et al.
JAMA Psychiatry Summary & key facts 2025 7 citations

This was a 6-week, double-blind, placebo-controlled trial that tested low-dose LSD (20 μg) given twice weekly in 53 adults with moderate to severe ADHD. Both the LSD group and the placebo group showed similar symptom reductions by week 6 (LSD mean change on the ADHD rating scale −7.1 points; placebo…

Attention Deficit Hyperactivity Disorder Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

What Are the Experiences of Adults With ADHD of Engaging in ADHD Medication Treatment? A Systematic Review and Meta-Ethnography

Lee Reeves, Anna Tickle

The review found that adults generally felt ADHD medications reduced their ADHD symptoms. But experiences differed a lot because of social, psychological, and physical side effects. People talked about taking medicines in the context of “fitting in” at school, work, and with family and friends. That idea of fitting in…

Attention Deficit Hyperactivity Disorder Neural and Behavioral Psychology Studies
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