Frontier mental health research: psychedelics & drug studies

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25 papers

Effects of voluntary slow breathing on heart rate and heart rate variability: A systematic review and a meta-analysis

Sylvain Laborde, Mark S. Allen, Uirassu Borges, Fabrice Dosseville, Thomas J. Hosang, Maša Iskra, et al.
PubMed Summary & key facts 2022 205 citations

This 2022 systematic review and meta-analysis pooled data from 223 studies to see if voluntary slow breathing (VSB) changes heart rate variability that reflects parasympathetic (vagal) control of the heart. The authors found that VSB increased vagally-mediated heart rate variability during breathing sessions, right after a single session, and after…

Cardiac Health and Mental Health Cardiovascular and exercise physiology Heart Rate Variability and Autonomic Control

Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome

Anthony J. Ocon
Frontiers in Physiology Summary & key facts 2013 151 citations

Chronic Fatigue Syndrome (CFS) is defined as more than 6 months of new, disabling physical and mental tiredness that is not relieved by rest. Up to about 85% of people with CFS report cognitive problems called “brain fog,” described as slow thinking, trouble focusing, confusion, forgetfulness, or a hazy mind.…

Fibromyalgia and Chronic Fatigue Syndrome Research Musculoskeletal pain and rehabilitation Olfactory and Sensory Function Studies

Benefits from one session of deep and slow breathing on vagal tone and anxiety in young and older adults

Valentin Magnon, Fréderic Dutheil, Guillaume T. Vallet
PubMed Summary & key facts 2021 124 citations

This clinical trial tested one session of deep and slow breathing (DSB) in 47 adults (22 older, 25 younger). After the single DSB session, high-frequency (HF) heart rate variability increased and self-reported state anxiety went down in both age groups. The rise in HF power was significantly larger in older…

Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Behavioral Health and Interventions Heart Rate Variability and Autonomic Control

Effects of Singing Bowl Sound Meditation on Mood, Tension, and Well-being: An Observational Study

Tamara L. Goldsby, Michael E. Goldsby, Mary McWalters, Paul J. Mills

This observational study tested Tibetan singing bowl sound meditation with 62 adults (mean age 49.7). After the session, people reported less tension, anger, fatigue, and depressed mood, and higher spiritual well-being. People who had never tried this meditation before showed a larger drop in tension than people who had experience.…

Music Therapy and Health Neuroscience and Music Perception Sleep and related disorders

Interactions between Stress and Vestibular Compensation – A Review

Yougan Saman, Doris‐Eva Bamiou, Michael Gleeson, Mayank B. Dutia
Frontiers in Neurology Summary & key facts 2012 80 citations

This review looked at studies in animals and people about how stress and the balance system (the vestibular system) affect each other. In many animal experiments, vestibular damage or stimulation turns on the body's stress system (the HPA axis) and short-term stress hormones help brain circuits adjust after vestibular loss.…

Circadian rhythm and melatonin Stress Responses and Cortisol Vestibular and auditory disorders

Improvement of cognitive functions by oral intake of <i>Hericium</i><i> erinaceus </i>

Yuusuke SAITSU, Akemi Nishide, Kenji Kikushima, Kuniyoshi Shimizu, Koichiro Ohnuki
Biomedical Research Summary & key facts 2019 74 citations

In a randomized, double-blind, placebo-controlled trial, people took supplements containing the mushroom Hericium erinaceus for 12 weeks. The researchers gave three mental tests and found that only the Mini-Mental State Examination (MMSE) showed a statistically significant improvement and less decline in the group taking the mushroom. The authors say compounds…

Fungal Biology and Applications Medicinal Plants and Bioactive Compounds Medicinal Plants and Neuroprotection

Vertigo/dizziness as a Drugs’ adverse reaction

Serafina Chimirri, Rossana Aiello, Carmela Mazzitello, Laura Mumoli, Caterina Palleria, Mariolina Altomonte, et al.

Spontaneous reports of vertigo or dizziness, as side-effect of certain drugs, received at our Pharmacovigilance Center, represented the 5% of all reports in 2012. Considering the high incidence of such an ADR for several drugs' classes, it can be speculated that under-reporting also affect vertigo and dizziness. Despite the fact…

Glaucoma and retinal disorders Neurological disorders and treatments Vestibular and auditory disorders

Progressive brain changes in patients with chronic fatigue syndrome: A longitudinal MRI study

Zack Shan, Richard Kwiatek, Richard Burnet, Peter Del Fante, Donald Staines, Sonya Marshall‐Gradisnik, et al.

The results suggested that CFS is associated with IFOF WM deficits which continue to deteriorate at an abnormal rate. J. Magn. Reson. Imaging 2016;44:1301-1311.

Fibromyalgia and Chronic Fatigue Syndrome Research Musculoskeletal pain and rehabilitation Psychosomatic Disorders and Their Treatments

Binaural beats to entrain the brain? A systematic review of the effects of binaural beat stimulation on brain oscillatory activity, and the implications for psychological research and intervention

Ruth Maria Ingendoh, Ella S. Posny, Angela Heine
PLoS ONE Summary & key facts 2023 70 citations

Binaural beats happen when two slightly different tones are played to each ear and you hear a third, pulsing tone at the difference between them. This review looked at 14 studies that measured brain activity after binaural-beat sounds. The results were mixed: some studies found brain activity that matched the…

Music Therapy and Health Neuroscience and Music Perception Phonocardiography and Auscultation Techniques

Ketamine effects on default mode network activity and vigilance: A randomized, placebo‐controlled crossover simultaneous fMRI/EEG study

Norman Zacharias, Francesco Musso, Felix Müller, Florian Lammers, Andreas Saleh, Markus K. London, et al.
Human Brain Mapping Summary & key facts 2019 65 citations

This randomized, double-blind, placebo-controlled crossover study gave subanesthetic S‑ketamine to 24 healthy young people while recording fMRI and EEG at rest. After ketamine, fMRI showed less connectivity in the medial prefrontal cortex and more connectivity in left and right intraparietal (parietal) areas of the default mode network. EEG showed more…

Functional Brain Connectivity Studies Neural and Behavioral Psychology Studies Treatment of Major Depression

Sound frequency affects speech emotion perception: results from congenital amusia

Sydney L. Lolli, Ari D. Lewenstein, Julian Basurto, Sean Winnik, Psyche Loui
Frontiers in Psychology Summary & key facts 2015 58 citations

This study tested whether people who are poor at hearing small pitch differences (congenital amusics) are worse at identifying emotions in speech. The researchers used normal speech, low-pass filtered speech (frequencies above ~500 Hz removed), and high-pass filtered speech (frequencies below ~4800 Hz removed). They found that worse pitch perception…

Hearing Loss and Rehabilitation Multisensory perception and integration Neuroscience and Music Perception
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