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Frontier mental health research: psychedelics & drug studies

Each month our editorial team sifts through hundreds of papers and curates notable findings—for practitioners and informed readers who want to stay current with the evidence. Subscribe to the monthly Research Digest for expert analysis and concise summaries of key papers.

Brief intervention

1 paper

Esketamine combined with a mindfulness-based intervention for individuals with alcohol problems

E.M. Van Gent, J. Bryan, M Cleary, Tegan I Clarke, Harry D Holmwood, Rania O Nassereddine, et al.
Journal of Psychopharmacology Summary & key facts 2024 13 citations

This small, double-blind pilot trial gave 28 people with alcohol problems either a sublingual esketamine film (115.1 mg) or a vitamin C placebo while they did two weeks of daily mindfulness practice. Compared with placebo, esketamine increased people’s psychological engagement with the meditation, produced stronger mystical and dissociative experiences, and…

Mindfulness and Compassion Interventions Treatment of Major Depression Tryptophan and brain disorders
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.